TB simple model

Name: Simple TB

Description: Framework for a simple TB model, without vital dynamics or new cases

Compartments

Compartment: Undiagnosed

  • Code name: undx

  • Does not appear in the databook

  • Description:

  • Data entry guidance:

Compartment: Diagnosed

  • Code name: dx

  • Does not appear in the databook

  • Description:

  • Data entry guidance:

Compartment: Notified and treated

  • Code name: tx

  • Does not appear in the databook

  • Description:

  • Data entry guidance:

Compartment: Lost to follow-up

  • Code name: lost

  • Does not appear in the databook

  • Description:

  • Data entry guidance:

Compartment: Successfully treated (comp)

  • Code name: txs

  • Does not appear in the databook

  • Description:

  • Data entry guidance:

Characteristics

Characteristic: TB burden

  • Code name: all_people

  • Value can be used for calibration

  • Includes:

    • Undiagnosed

    • Diagnosed

    • Notified and treated

    • Lost to follow-up

    • Successfully treated (comp)

  • Appears in the databook

  • Databook values will be used for model initialization

  • Description:

  • Data entry guidance:

Characteristic: Notified

  • Code name: all_dx

  • Value can be used for calibration

  • Includes:

    • Diagnosed

    • Notified and treated

    • Lost to follow-up

    • Successfully treated (comp)

  • Appears in the databook

  • Databook values will be used for model initialization

  • Description:

  • Data entry guidance:

Characteristic: In care

  • Code name: all_curr_linked

  • Value can be used for calibration

  • Includes:

    • Diagnosed

    • Notified and treated

    • Successfully treated (comp)

  • Appears in the databook

  • Databook values will be used for model initialization

  • Description:

  • Data entry guidance:

Characteristic: Treated

  • Code name: all_tx

  • Value can be used for calibration

  • Includes:

    • Notified and treated

    • Successfully treated (comp)

  • Appears in the databook

  • Databook values will be used for model initialization

  • Description:

  • Data entry guidance:

Characteristic: Successfully treated

  • Code name: all_vs

  • Value can be used for calibration

  • Includes:

    • Successfully treated (comp)

  • Appears in the databook

  • Databook values will be used for model initialization

  • Description:

  • Data entry guidance:

Parameters

Parameter: Annual number of tests done

  • Code name: num_test

  • Units/format: number

  • Value restrictions: At least 0

  • Default value: None

  • Appears in the databook

  • Used to compute:

    • “Annual number tested positive”

  • Description:

  • Data entry guidance:

Parameter: Test yield

  • Code name: test_yield

  • Units/format: probability

  • Value restrictions: 0-1.0000

  • Default value: None

  • Appears in the databook

  • Used to compute:

    • “Annual number tested positive”

  • Description:

  • Data entry guidance:

Parameter: Annual number tested positive

  • Code name: pos_test

  • Units/format: number

  • Value restrictions: At least 0

  • Default value: None

  • Does not appear in the databook

  • This parameter’s value is computed by a function: num_test*test_yield

  • Depends on:

    • “Annual number of tests done”

    • “Test yield”

  • Used to compute:

    • “Test sensitivity”

  • Description:

  • Data entry guidance:

Parameter: Test sensitivity

  • Code name: diag

  • Value can be used for calibration

  • Units/format: probability

  • Value restrictions: 0-1.0000

  • Contributes to transitions from:

    • “Undiagnosed” to “Diagnosed”

  • Default value: None

  • Does not appear in the databook

  • This parameter’s value is computed by a function: pos_test/max(undx,pos_test)

  • Depends on:

    • “Undiagnosed”

    • “Annual number tested positive”

  • Description:

  • Data entry guidance:

Parameter: Annual number newly initiated onto treatment

  • Code name: num_initiate

  • Units/format: number

  • Value restrictions: At least 0

  • Default value: None

  • Appears in the databook

  • Used to compute:

    • “Initiation rate”

  • Description:

  • Data entry guidance:

Parameter: Initiation rate

  • Code name: initiate

  • Value can be used for calibration

  • Units/format: probability

  • Value restrictions: 0-1.0000

  • Contributes to transitions from:

    • “Diagnosed” to “Notified and treated”

    • “Lost to follow-up” to “Notified and treated”

  • Default value: None

  • Does not appear in the databook

  • This parameter’s value is computed by a function: num_initiate/max(dx,num_initiate)

  • Depends on:

    • “Diagnosed”

    • “Annual number newly initiated onto treatment”

  • Description:

  • Data entry guidance:

Parameter: Loss-to-follow-up rate

  • Code name: loss

  • Value can be used for calibration

  • Units/format: probability

  • Value restrictions: 0-1.0000

  • Contributes to transitions from:

    • “Notified and treated” to “Lost to follow-up”

    • “Successfully treated (comp)” to “Lost to follow-up”

  • Default value: None

  • Appears in the databook

  • Description:

  • Data entry guidance:

Parameter: Time after initiating treatment to treatment success (years)

  • Code name: succ_rate

  • Units/format: duration

  • Value restrictions: At least 0

  • Contributes to transitions from:

    • “Notified and treated” to “Successfully treated (comp)”

  • Default value: 0.2

  • Appears in the databook

  • Description:

  • Data entry guidance:

Parameter: Treatment failure rate

  • Code name: fail_rate

  • Value can be used for calibration

  • Units/format: probability

  • Value restrictions: 0-1.0000

  • Contributes to transitions from:

    • “Successfully treated (comp)” to “Notified and treated”

  • Default value: 0.16

  • Appears in the databook

  • Description:

  • Data entry guidance:

Interactions

Cascades

Cascade: TB care cascade

  • Description:

  • Stages:

    • TB burden

      • TB burden

    • Notified

      • Notified

    • In care

      • In care

    • Treated

      • Treated

    • Successfully treated

      • Successfully treated